Reta 10 mg

Retatrutide is a novel investigational drug developed by Eli Lilly that acts as a triple agonist of:

GLP-1 (glucagon-like peptide-1)

GIP (glucose-dependent insulinotropic polypeptide)

Glucagon receptors

It’s primarily being studied for obesity, type 2 diabetes, and nonalcoholic fatty liver disease (NAFLD). However, because of its potent metabolic effects, it's gaining attention for potential performance-enhancing benefits, particularly in the realms of body composition and metabolic efficiency.

Potential Performance-Enhancing Benefits of Retatrutide

1. Significant Fat Loss

Clinical trials have shown up to ~24% weight loss over 48–72 weeks, most of it being body fat.

This can improve power-to-weight ratio, especially beneficial in endurance and weight-class sports.

2. Improved Insulin Sensitivity

Retatrutide enhances insulin sensitivity and glucose disposal.

This helps with stable energy levels and potentially better muscle glycogen replenishment.

3. Appetite Suppression and Craving Reduction

Reduced caloric intake without subjective hunger can help athletes maintain a leaner physique while training hard.

4. Improved Mitochondrial Efficiency and Fat Oxidation (Theoretical/Indirect)

By activating glucagon receptors, it may promote lipolysis and mitochondrial biogenesis, enhancing endurance performance.

However, this is more hypothetical and not yet well studied in athletes.

5. Potential Anti-Inflammatory Effects

GLP-1 agonists may reduce low-grade systemic inflammation, possibly aiding recovery and reducing muscle soreness.

Important Caveats and Considerations

Muscle Mass Preservation: There’s a concern (based on similar GLP-1 drugs) that weight loss includes some lean mass, although combining it with resistance training may mitigate this.

Energy Levels: Reduced appetite and caloric intake might lead to lower energy availability, which can impair performance, especially in strength or power sports.

Not Approved for Athletic Use: It’s an investigational drug, not approved for general use, and may be prohibited under WADA (World Anti-Doping Agency) rules if found performance enhancing.

Side Effects: GI symptoms (nausea, diarrhea), fatigue, and potential thyroid concerns (based on rodent studies) are notable risks.

⚠️ Disclaimer: This compound is offered for laboratory research purposes only. It is not approved for medical, clinical, or diagnostic use in humans or animals.