Molecular Formula: C₁₈H₁₄N₂O₂
Molecular Weight: 290.3
SLU-PP-332 is a small-molecule compound identified as an ERR (Estrogen-Related Receptor) agonist, particularly targeting ERRβ/γ receptors. It was developed and studied primarily in the context of metabolic and mitochondrial function. Though it's not a mainstream or clinically approved drug, some preclinical research, including rodent studies, suggests it may have performance-enhancing properties due to its impact on energy metabolism.
Key Performance-Enhancing Benefits of SLU-PP-332 (Based on Preclinical Research):
Enhanced Mitochondrial Biogenesis
SLU-PP-332 activates ERRβ and ERRγ, which are nuclear receptors that regulate genes involved in mitochondrial function.This leads to increased mitochondrial number and improved oxidative capacity in muscle cells.
Improved Endurance
Animal studies (e.g., in mice) show improved treadmill running time and distance.
Likely due to improved oxidative metabolism and energy efficiency in skeletal muscle.
Increased Fatty Acid Oxidation
ERRγ activation shifts energy metabolism from glycolysis to oxidative phosphorylation and fat burning.
This mimics some effects of endurance training or fasting.
Exercise Mimetic Effects
It has been described as an "exercise mimetic" because it can induce some of the gene expression profiles associated with aerobic exercise, without physical activity.
Potential for Muscle Sparing
While not definitively proven, improved mitochondrial efficiency and fat utilization could support muscle preservation under stress.
Important Caveats:
No Human Trials Yet: All known research is in rodents or cell cultures. Human effects are unknown.
Regulatory Status: Not approved for medical or athletic use. Likely prohibited by anti-doping agencies if detected.
Potential Risks: Unknown side effects or long-term risks due to lack of clinical data.
Summary
SLU-PP-332 may enhance endurance and metabolic performance in preclinical models by boosting mitochondrial function and fat oxidation. However, it remains experimental, with no human data, and should be approached with caution outside a research setting.
⚠️ Disclaimer: This compound is offered for laboratory research purposes only. It is not approved for medical, clinical, or diagnostic use in humans or animals.